Nomascus leucogenys      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 37 genes.  Reviewed (0 or Unreviewed (37

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nol-2840
ENSNLEG00000030377.1
A0A2I3HB01
2
LLPS-Nol-4543
ENSNLEG00000000145.3
G1QGY7
3
LLPS-Nol-1379
ENSNLEG00000007029.3
G1R5V0
AURKA
4
LLPS-Nol-1384
ENSNLEG00000001715.2
G1QMG6
CDC6
5
LLPS-Nol-2181
ENSNLEG00000035058.1
A0A2I3HP74
CHAMP1
6
LLPS-Nol-2337
ENSNLEG00000015724.3
G1S0R1
CKAP2
7
LLPS-Nol-1306
ENSNLEG00000014160.3
A0A2I3GBS0
CKAP5
8
LLPS-Nol-1398
ENSNLEG00000012503.3
G1RPL6
CLTB
9
LLPS-Nol-1874
ENSNLEG00000004861.3
A0A2I3GTA3
DCTN3
10
LLPS-Nol-3577
ENSNLEG00000012807.3
A0A2I3HSI1
DLGAP5
11
LLPS-Nol-0976
ENSNLEG00000016244.3
G1S2J3
DPYSL2
12
LLPS-Nol-2474
ENSNLEG00000000742.3
M3Z9X3
DYRK3
13
LLPS-Nol-4116
ENSNLEG00000012157.3
G1RNK7
FES
14
LLPS-Nol-2115
ENSNLEG00000002053.2
G1QNT0
GPSM2
15
LLPS-Nol-4117
ENSNLEG00000017550.3
G1S718
HAUS6
16
LLPS-Nol-1967
ENSNLEG00000009746.2
G1RF64
KAT14
17
LLPS-Nol-0889
ENSNLEG00000000679.3
G1QIT4
KATNAL1
18
LLPS-Nol-0272
ENSNLEG00000012674.2
G1RQ95
KIF11
19
LLPS-Nol-1085
ENSNLEG00000009092.3
G1RCX9
MAD2L1
20
LLPS-Nol-1543
ENSNLEG00000009647.2
G1REU0
MAD2L2
21
LLPS-Nol-3342
ENSNLEG00000006476.3
G1R3W5
MAPK6
22
LLPS-Nol-0442
ENSNLEG00000006280.3
G1R377
MAPRE2
23
LLPS-Nol-2344
ENSNLEG00000016447.2
A0A2I3GHZ4
MKNK1
24
LLPS-Nol-2436
ENSNLEG00000009578.3
A0A2I3GRH0
MTOR
25
LLPS-Nol-3593
ENSNLEG00000035317.1
A0A2I3GV23
NCOA4
26
LLPS-Nol-3372
ENSNLEG00000007066.2
G1R5Y7
PARD3B
27
LLPS-Nol-1084
ENSNLEG00000012258.3
A0A2I3H8N1
PRC1
28
LLPS-Nol-2879
ENSNLEG00000004851.2
A0A2I3HNX1
RANBP10
29
LLPS-Nol-3753
ENSNLEG00000012505.2
G1RPN1
RBPMS2
30
LLPS-Nol-1202
ENSNLEG00000007247.3
G1R6L7
RDX
31
LLPS-Nol-0617
ENSNLEG00000013873.3
A0A2I3H7I7
SEPT2
32
LLPS-Nol-1791
ENSNLEG00000015486.3
M3Z9R5
SMC3
33
LLPS-Nol-0588
ENSNLEG00000008323.3
G1RAI6
SUN1
34
LLPS-Nol-1170
ENSNLEG00000015173.2
G1RYX5
SUN2
35
LLPS-Nol-4163
ENSNLEG00000004174.3
G1QVU5
TADA3
36
LLPS-Nol-0593
ENSNLEG00000009292.3
G1RDM1
TMEM201
37
LLPS-Nol-2092
ENSNLEG00000005954.3
A0A2I3HK00
ZNF207