Mus musculus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 38 genes.  Reviewed (16 or Unreviewed (22

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mum-2044
ENSMUSG00000017499.15
O89033
Cdc6
2
LLPS-Mum-3828
ENSMUSG00000040549.16
A2AGT5
Ckap5
3
LLPS-Mum-3402
ENSMUSG00000047547.14
Q6IRU5
Cltb
4
LLPS-Mum-0479
ENSMUSG00000028447.11
Q9Z0Y1
Dctn3
5
LLPS-Mum-2770
ENSMUSG00000037544.14
Q8K4R9
Dlgap5
6
LLPS-Mum-1917
ENSMUSG00000022048.8
O08553
Dpysl2
7
LLPS-Mum-2657
ENSMUSG00000053158.10
P16879
Fes
8
LLPS-Mum-0021
ENSMUSG00000027425.18
Q8CID0
Kat14
9
LLPS-Mum-1530
ENSMUSG00000042688.16
Q61532
Mapk6
10
LLPS-Mum-1481
ENSMUSG00000027479.14
Q61166
Mapre1
11
LLPS-Mum-1400
ENSMUSG00000044345.9
Q7TQJ1
Marveld1
12
LLPS-Mum-4690
ENSMUSG00000031207.16
P26041
Msn
13
LLPS-Mum-1820
ENSMUSG00000025812.17
Q99NH2
Pard3
14
LLPS-Mum-1915
ENSMUSG00000026276.20
P42208
Sept2
15
LLPS-Mum-2977
ENSMUSG00000048930.12
Q8R0L9
Tada3
16
LLPS-Mum-3351
ENSMUSG00000062380.4
Q9ERD7
Tubb3
17
LLPS-Mum-2927
ENSMUSG00000047710.8
Q8K327
Champ1
18
LLPS-Mum-4643
ENSMUSG00000037725.8
Q3V1H1
Ckap2
19
LLPS-Mum-3320
ENSMUSG00000016526.8
Q922Y0
Dyrk3
20
LLPS-Mum-3589
ENSMUSG00000027883.15
Q8VDU0
Gpsm2
21
LLPS-Mum-4607
ENSMUSG00000079555.2
Q8QZX2
Haus3
22
LLPS-Mum-3730
ENSMUSG00000038047.18
Q6NV99
Haus6
23
LLPS-Mum-3049
ENSMUSG00000019794.13
Q9WV86
Katna1
24
LLPS-Mum-1650
ENSMUSG00000012443.3
Q6P9P6
Kif11
25
LLPS-Mum-1002
ENSMUSG00000029910.14
Q9Z1B5
Mad2l1
26
LLPS-Mum-3747
ENSMUSG00000029003.11
Q9D752
Mad2l2
27
LLPS-Mum-0706
ENSMUSG00000028708.16
O08605
Mknk1
28
LLPS-Mum-1653
ENSMUSG00000028991.15
Q9JLN9
Mtor
29
LLPS-Mum-4235
ENSMUSG00000045636.16
Q5HZI1
Mtus1
30
LLPS-Mum-3598
ENSMUSG00000056234.15
Q5U4H9
Ncoa4
31
LLPS-Mum-3062
ENSMUSG00000037415.6
Q6VN19
Ranbp10
32
LLPS-Mum-4570
ENSMUSG00000031586.17
Q9WVB0
Rbpms
33
LLPS-Mum-0564
ENSMUSG00000024974.10
Q9CW03
Smc3
34
LLPS-Mum-3961
ENSMUSG00000042524.14
Q8BJS4
Sun2
35
LLPS-Mum-3633
ENSMUSG00000044700.15
A2A8U2
Tmem201
36
LLPS-Mum-0915
ENSMUSG00000006005.18
F6ZDS4
Tpr
37
LLPS-Mum-1540
ENSMUSG00000018750.14
Q5F293
Zbtb4
38
LLPS-Mum-3155
ENSMUSG00000017421.18
Q9JMD0
Znf207