Macaca mulatta      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 40 genes.  Reviewed (0 or Unreviewed (40

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mam-0218
ENSMMUG00000039047.1
A0A1D5QZV0
2
LLPS-Mam-0427
ENSMMUG00000040035.1
A0A1D5R9A4
3
LLPS-Mam-1921
ENSMMUG00000000070.3
F7GNU0
AURKA
4
LLPS-Mam-2132
ENSMMUG00000002997.3
F6VVA5
AURKB
5
LLPS-Mam-2310
ENSMMUG00000004755.3
F6SMW5
CDC6
6
LLPS-Mam-2025
ENSMMUG00000023599.3
G7NJP8
CHAMP1
7
LLPS-Mam-3184
ENSMMUG00000018720.3
F6YBX6
CKAP2
8
LLPS-Mam-1181
ENSMMUG00000003631.3
H9Z1V0
CKAP5
9
LLPS-Mam-1959
ENSMMUG00000009058.3
H9FPR6
CLTB
10
LLPS-Mam-0640
ENSMMUG00000023140.3
H9FXK3
CSRP2BP
11
LLPS-Mam-3223
ENSMMUG00000020782.3
F7HA44
DCTN3
12
LLPS-Mam-1706
ENSMMUG00000003567.3
F7ETD4
DLGAP5
13
LLPS-Mam-0770
ENSMMUG00000012718.3
A0A1D5QW32
DPYSL2
14
LLPS-Mam-2622
ENSMMUG00000023566.3
F7FZF8
DYRK3
15
LLPS-Mam-3376
ENSMMUG00000004659.3
G7MVY9
FES
16
LLPS-Mam-1391
ENSMMUG00000010161.3
H9FTK2
GPSM2
17
LLPS-Mam-4691
ENSMMUG00000001158.3
F6RPM9
HAUS3
18
LLPS-Mam-3142
ENSMMUG00000018396.3
F7GZC3
HAUS6
19
LLPS-Mam-0756
ENSMMUG00000004922.3
F6Y7A7
KATNAL1
20
LLPS-Mam-1712
ENSMMUG00000023266.3
F7FKH9
KIF11
21
LLPS-Mam-3383
ENSMMUG00000023669.3
H9EQN4
MAD2L2
22
LLPS-Mam-0166
ENSMMUG00000029652.2
F7GB31
MAPK6
23
LLPS-Mam-0076
ENSMMUG00000019921.2
H9H444
MARVELD1
24
LLPS-Mam-0172
ENSMMUG00000020162.3
F6TJU6
MKNK1
25
LLPS-Mam-2102
ENSMMUG00000015653.3
F6RKX8
MSN
26
LLPS-Mam-0198
ENSMMUG00000019325.3
H9ENS2
MTOR
27
LLPS-Mam-2313
ENSMMUG00000001151.3
H9FXM6
MTUS1
28
LLPS-Mam-0895
ENSMMUG00000015182.3
F6WBK7
NCOA4
29
LLPS-Mam-0722
ENSMMUG00000019156.3
F7HHT6
PARD3
30
LLPS-Mam-4661
ENSMMUG00000007804.3
A0A1D5RII8
RANBP10
31
LLPS-Mam-0833
ENSMMUG00000014166.3
F6XVQ7
RANGAP1
32
LLPS-Mam-2229
ENSMMUG00000000458.3
F6YR70
RBPMS
33
LLPS-Mam-1153
ENSMMUG00000004736.3
F6R3X6
SEPT2
34
LLPS-Mam-0222
ENSMMUG00000007982.3
A0A1D5R8F6
SMC3
35
LLPS-Mam-2035
ENSMMUG00000017056.3
F7HLL7
SUN1
36
LLPS-Mam-2604
ENSMMUG00000007284.3
I2CYJ6
SUN2
37
LLPS-Mam-1280
ENSMMUG00000006114.3
F7B699
TADA3
38
LLPS-Mam-0339
ENSMMUG00000009081.3
F7EEB8
TPR
39
LLPS-Mam-0276
ENSMMUG00000023616.3
G7NIF6
ZBTB4
40
LLPS-Mam-4460
ENSMMUG00000016875.3
F7BQE6
ZNF207