Loxodonta africana      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 38 genes.  Reviewed (0 or Unreviewed (38

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Loa-4214
ENSLAFG00000017181.3
G3TID4
2
LLPS-Loa-2197
ENSLAFG00000000608.2
G3SM21
CDC6
3
LLPS-Loa-0044
ENSLAFG00000003333.4
G3SS62
CHAMP1
4
LLPS-Loa-0444
ENSLAFG00000010386.3
G3TR83
CKAP5
5
LLPS-Loa-3605
ENSLAFG00000026300.1
G3U1R1
CLTB
6
LLPS-Loa-1903
ENSLAFG00000017908.2
G3TJS5
DCTN3
7
LLPS-Loa-1801
ENSLAFG00000005169.3
G3U2N6
DLGAP5
8
LLPS-Loa-0186
ENSLAFG00000003305.3
G3SS47
DPYSL2
9
LLPS-Loa-3579
ENSLAFG00000004569.3
G3SUH6
DYRK3
10
LLPS-Loa-2631
ENSLAFG00000005977.4
G3SX96
FES
11
LLPS-Loa-2112
ENSLAFG00000004284.4
G3STY9
GPSM2
12
LLPS-Loa-4194
ENSLAFG00000020863.3
G3TM40
HAUS3
13
LLPS-Loa-4241
ENSLAFG00000011084.3
G3T6U9
HAUS6
14
LLPS-Loa-1385
ENSLAFG00000005652.2
G3SWN1
KAT14
15
LLPS-Loa-2601
ENSLAFG00000003140.4
G3SRS3
KATNAL1
16
LLPS-Loa-0728
ENSLAFG00000015454.3
G3TF73
KIF11
17
LLPS-Loa-0132
ENSLAFG00000029619.1
G3TM64
LOC100668722
18
LLPS-Loa-3722
ENSLAFG00000016259.2
G3TGM9
MAD2L2
19
LLPS-Loa-3031
ENSLAFG00000013900.3
G3TC81
MAPK6
20
LLPS-Loa-1425
ENSLAFG00000015453.3
G3TF67
MAPRE1
21
LLPS-Loa-1058
ENSLAFG00000015556.3
G3TWS6
MKNK1
22
LLPS-Loa-3296
ENSLAFG00000015635.4
G3TFL3
MTOR
23
LLPS-Loa-3220
ENSLAFG00000009785.4
G3T4C7
MTUS1
24
LLPS-Loa-2768
ENSLAFG00000000872.3
G3SMI2
NCOA4
25
LLPS-Loa-3616
ENSLAFG00000018145.3
G3TK86
PARD3
26
LLPS-Loa-3320
ENSLAFG00000013123.3
G3TAR2
PRC1
27
LLPS-Loa-2604
ENSLAFG00000007130.3
G3SZF8
RANBP10
28
LLPS-Loa-1354
ENSLAFG00000000209.3
G3SL98
RBPMS
29
LLPS-Loa-0036
ENSLAFG00000014920.3
G3TE54
RDX
30
LLPS-Loa-0788
ENSLAFG00000011964.4
G3TXC5
SEPT2
31
LLPS-Loa-1824
ENSLAFG00000014862.3
G3TE12
SMC3
32
LLPS-Loa-3165
ENSLAFG00000015996.3
G3TG49
SUN1
33
LLPS-Loa-1589
ENSLAFG00000010302.4
G3T5D1
SUN2
34
LLPS-Loa-2002
ENSLAFG00000017494.3
G3TIZ7
TADA3
35
LLPS-Loa-0778
ENSLAFG00000022369.2
G3U7H6
TMEM201
36
LLPS-Loa-0106
ENSLAFG00000005329.4
G3SW16
TPR
37
LLPS-Loa-1552
ENSLAFG00000015214.3
G3TEP8
ZBTB4
38
LLPS-Loa-4431
ENSLAFG00000004317.3
G3SU14
ZNF207