Ciona savignyi      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cis-0004
ENSCSAVG00000009302.1
H2ZE05
2
LLPS-Cis-0074
ENSCSAVG00000007093.1
H2Z393
3
LLPS-Cis-0078
ENSCSAVG00000001974.1
H2YDB2
4
LLPS-Cis-0269
ENSCSAVG00000003336.1
H2YJT0
5
LLPS-Cis-0349
ENSCSAVG00000004560.1
H2YQM0
6
LLPS-Cis-0492
ENSCSAVG00000006888.1
H2Z2D4
7
LLPS-Cis-0589
ENSCSAVG00000006087.1
H2YYC5
8
LLPS-Cis-0959
ENSCSAVG00000001715.1
H2YC31
9
LLPS-Cis-1119
ENSCSAVG00000010424.1
H2ZJE5
10
LLPS-Cis-1152
ENSCSAVG00000003688.1
H2YLH9
11
LLPS-Cis-1177
ENSCSAVG00000005114.1
H2YTE0
12
LLPS-Cis-1237
ENSCSAVG00000001779.1
H2YCD3
13
LLPS-Cis-1302
ENSCSAVG00000006596.1
H2Z111
14
LLPS-Cis-1330
ENSCSAVG00000005707.1
H2YWL4
15
LLPS-Cis-1493
ENSCSAVG00000005528.1
H2YVL6
16
LLPS-Cis-2043
ENSCSAVG00000006204.1
H2YYZ0
17
LLPS-Cis-2074
ENSCSAVG00000010840.1
H2ZLJ4
18
LLPS-Cis-0514
ENSCSAVG00000002933.1
H2YHY0
KATNA1