Cavia porcellus      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 35 genes.  Reviewed (0 or Unreviewed (35

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cap-0539
ENSCPOG00000006633.4
H0V884
Aurka
2
LLPS-Cap-3580
ENSCPOG00000010305.4
H0VGK9
CDC6
3
LLPS-Cap-1278
ENSCPOG00000012382.4
H0VLB1
CKAP2
4
LLPS-Cap-0096
ENSCPOG00000007054.4
A0A286Y0W1
CKAP5
5
LLPS-Cap-2461
ENSCPOG00000035873.1
A0A286XPF9
CLTB
6
LLPS-Cap-1253
ENSCPOG00000001540.4
A0A286XNI0
DCTN3
7
LLPS-Cap-1862
ENSCPOG00000004807.4
A0A286XI62
DLGAP5
8
LLPS-Cap-4203
ENSCPOG00000025679.2
H0W639
DPYSL2
9
LLPS-Cap-1669
ENSCPOG00000024699.2
H0WAZ0
DYRK3
10
LLPS-Cap-3255
ENSCPOG00000021994.2
H0W6Q8
HAUS3
11
LLPS-Cap-2327
ENSCPOG00000013124.4
A0A286XJH9
KAT14
12
LLPS-Cap-3139
ENSCPOG00000000804.4
H0UUS0
KATNAL1
13
LLPS-Cap-2543
ENSCPOG00000021736.2
A0A286XZD1
KIF11
14
LLPS-Cap-0255
ENSCPOG00000030145.1
A0A286Y2Z1
MAD2L1
15
LLPS-Cap-0423
ENSCPOG00000022099.2
H0W3M3
MAD2L2
16
LLPS-Cap-2806
ENSCPOG00000035029.1
A0A286XHY3
MAPK6
17
LLPS-Cap-0840
ENSCPOG00000023542.2
H0W6T7
Mapre1
18
LLPS-Cap-2051
ENSCPOG00000024434.2
H0VYT2
MARVELD1
19
LLPS-Cap-2289
ENSCPOG00000035798.1
A0A286XU16
Mknk1
20
LLPS-Cap-3285
ENSCPOG00000007103.4
A0A286Y111
MSN
21
LLPS-Cap-1515
ENSCPOG00000011641.4
H0VJM9
MTOR
22
LLPS-Cap-4657
ENSCPOG00000008656.4
H0VCU6
MTUS1
23
LLPS-Cap-1948
ENSCPOG00000011259.4
H0VIS1
NCOA4
24
LLPS-Cap-0148
ENSCPOG00000015693.4
H0VTY4
PARD3
25
LLPS-Cap-1955
ENSCPOG00000010735.4
A0A286XBA8
RANBP10
26
LLPS-Cap-1909
ENSCPOG00000038597.1
A0A286XJN5
RBPMS
27
LLPS-Cap-0714
ENSCPOG00000013687.4
H0VPA8
Sept2
28
LLPS-Cap-1275
ENSCPOG00000008978.4
H0VDK8
SMC3
29
LLPS-Cap-2933
ENSCPOG00000005965.4
H0V6Q8
SUN2
30
LLPS-Cap-0240
ENSCPOG00000014236.4
H0VQK0
SUN3
31
LLPS-Cap-0904
ENSCPOG00000007692.4
H0VAP1
TADA3
32
LLPS-Cap-3606
ENSCPOG00000026442.2
A0A286XYF6
TMEM201
33
LLPS-Cap-0822
ENSCPOG00000019790.2
H0WA32
TPR
34
LLPS-Cap-0959
ENSCPOG00000033470.1
A0A286Y1P3
ZBTB4
35
LLPS-Cap-2892
ENSCPOG00000001728.4
A0A286X7C2
ZNF207