Ailuropoda melanoleuca      Spindle apparatus


※ Spindle apparatus introduction

    The spindle is an important structure when cells divide. Phase separation promotes the concentration of molecules into the droplets, thereby promoting biochemical reactions. Some protein mixtures undergo a phase change to form droplets that concentrate actin to promote F-actin assembly in vitro. In addition, studies have shown that the phase transition of spindle regulatory protein BuGZ concentrates tubulin and promotes MT polymerizationbinds to tubulin and promotes spindle assembly (1).

Reference
1. Jiang, H., Wang, S., Huang, Y., He, X., Cui, H., Zhu, X., & Zheng, Y. (2015) Phase transition of spindle-associated protein regulate spindle apparatus assembly. Cell, 163(1), 108-122. PMID: 26388440


There are 36 genes.  Reviewed (0 or Unreviewed (36

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aim-0090
ENSAMEG00000003048.1
G1L8I4
2
LLPS-Aim-2281
ENSAMEG00000015671.1
G1MB25
3
LLPS-Aim-0753
ENSAMEG00000007168.1
G1LKV1
AURKA
4
LLPS-Aim-1722
ENSAMEG00000004936.1
G1LEA0
AURKC
5
LLPS-Aim-0757
ENSAMEG00000007868.1
G1LMR5
CDC6
6
LLPS-Aim-3988
ENSAMEG00000019446.1
D2HTR1
CHAMP1
7
LLPS-Aim-2057
ENSAMEG00000011827.1
G1LZD1
CKAP2
8
LLPS-Aim-1296
ENSAMEG00000006979.1
G1LKH1
CKAP5
9
LLPS-Aim-2531
ENSAMEG00000007003.1
G1LKC3
CLTB
10
LLPS-Aim-1599
ENSAMEG00000014592.1
G1M7R7
DCTN3
11
LLPS-Aim-1148
ENSAMEG00000007001.1
G1LKD8
DLGAP5
12
LLPS-Aim-0482
ENSAMEG00000000223.1
G1L094
DPYSL2
13
LLPS-Aim-2571
ENSAMEG00000004449.1
G1LCV7
GPSM2
14
LLPS-Aim-2833
ENSAMEG00000014332.1
D2H4G1
HAUS3
15
LLPS-Aim-3524
ENSAMEG00000002777.1
G1L7U7
HAUS6
16
LLPS-Aim-3004
ENSAMEG00000005253.1
G1LF67
KAT14
17
LLPS-Aim-0039
ENSAMEG00000008885.1
G1LQL6
KATNAL1
18
LLPS-Aim-0404
ENSAMEG00000014099.1
G1M6D1
KIF11
19
LLPS-Aim-4017
ENSAMEG00000009747.1
G1LT52
MAD2L2
20
LLPS-Aim-0278
ENSAMEG00000007132.1
D2HN70
MAPK6
21
LLPS-Aim-0727
ENSAMEG00000013238.1
G1M3N9
MAPRE1
22
LLPS-Aim-1917
ENSAMEG00000000095.1
G1KZP7
MARVELD1
23
LLPS-Aim-2218
ENSAMEG00000014008.1
G1M620
MKNK1
24
LLPS-Aim-4376
ENSAMEG00000001586.1
D2I4R2
MSN
25
LLPS-Aim-3401
ENSAMEG00000013652.1
G1M4Y5
MTUS1
26
LLPS-Aim-4196
ENSAMEG00000007503.1
G1LLV2
NCOA4
27
LLPS-Aim-3244
ENSAMEG00000017511.1
G1MGM7
RANBP10
28
LLPS-Aim-3302
ENSAMEG00000001522.1
G1L3Z7
RBPMS
29
LLPS-Aim-1019
ENSAMEG00000016539.1
G1MDP9
SEPT2
30
LLPS-Aim-1168
ENSAMEG00000015675.1
G1MB71
SMC3
31
LLPS-Aim-1573
ENSAMEG00000005870.1
G1LH55
SUN1
32
LLPS-Aim-2628
ENSAMEG00000010757.1
G1LW79
SUN2
33
LLPS-Aim-2180
ENSAMEG00000016252.1
D2HRA8
TADA3
34
LLPS-Aim-4041
ENSAMEG00000004023.1
G1LBH2
TMEM201
35
LLPS-Aim-2485
ENSAMEG00000015423.1
G1MAI0
TPR
36
LLPS-Aim-3347
ENSAMEG00000005671.1
G1LGF5
ZNF207