Xenopus tropicalis      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Xet-1542
ENSXETG00000012569.3
Q537I0
hnrnpd
2
LLPS-Xet-2298
ENSXETG00000011722.2
F7CSL3
hnrnpk
3
LLPS-Xet-3395
ENSXETG00000000037.3
F6V4Z5
hnrnpl
4
LLPS-Xet-0337
ENSXETG00000005246.3
F6VEI6
khdrbs1
5
LLPS-Xet-1962
ENSXETG00000004451.3
Q0VFL3
khdrbs2
6
LLPS-Xet-2517
ENSXETG00000009227.3
F7DUZ1
khdrbs3
7
LLPS-Xet-0876
ENSXETG00000016495.3
Q6P7N1
mak16
8
LLPS-Xet-0163
ENSXETG00000014562.3
Q28IV8
ngdn
9
LLPS-Xet-2989
ENSXETG00000003481.3
F6ZWI8
rbmx
10
LLPS-Xet-3829
ENSXETG00000018189.3
F7AWW9
smn2
11
LLPS-Xet-1531
ENSXETG00000017960.3
F6XU94
ythdc1