Tursiops truncatus      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tut-0995
ENSTTRG00000004505.1
A0A2U4CBH8
HNRNPA1
2
LLPS-Tut-0451
ENSTTRG00000004906.1
A0A2U4BS49
HNRNPK
3
LLPS-Tut-0144
ENSTTRG00000009637.1
A0A2U3V478
KHDRBS1
4
LLPS-Tut-0714
ENSTTRG00000005591.1
A0A2U4B1M5
KHDRBS2
5
LLPS-Tut-0677
ENSTTRG00000001270.1
A0A2U4B2X6
KHDRBS3
6
LLPS-Tut-2394
ENSTTRG00000005080.1
A0A2U4AWX6
LOC101330346
7
LLPS-Tut-0517
ENSTTRG00000013015.1
A0A2U3V6Z9
MAK16
8
LLPS-Tut-0208
ENSTTRG00000010655.2
A0A2U3V4E6
NGDN
9
LLPS-Tut-0428
ENSTTRG00000007322.1
A0A2U4A0L0
RBMX
10
LLPS-Tut-2285
ENSTTRG00000002742.1
A0A2U4CGL5
TLE4
11
LLPS-Tut-0829
ENSTTRG00000005083.1
A0A2U4ARR2
YTHDC1