Takifugu rubripes      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tar-0016
ENSTRUG00000010142.2
H2TLH8
2
LLPS-Tar-2327
ENSTRUG00000010659.2
H2TQE9
hnrnpk
3
LLPS-Tar-1589
ENSTRUG00000010649.2
H2TQC2
hnrnpl
4
LLPS-Tar-0477
ENSTRUG00000015760.2
H2UTK1
khdrbs2
5
LLPS-Tar-0265
ENSTRUG00000013451.2
H2UBH5
KHDRBS3
6
LLPS-Tar-0189
ENSTRUG00000010001.2
H2TKF9
LOC101062326
7
LLPS-Tar-1670
ENSTRUG00000018450.2
H2VDE0
LOC101066421
8
LLPS-Tar-0659
ENSTRUG00000011544.2
H2TWV2
mak16
9
LLPS-Tar-0514
ENSTRUG00000006677.2
A0A3B5KHN0
ngdn
10
LLPS-Tar-2310
ENSTRUG00000000736.2
H2RNQ5
smn
11
LLPS-Tar-1007
ENSTRUG00000016796.2
Q3LFR4
TLE3