Sarcophilus harrisii      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 12 genes.  Reviewed (0 or Unreviewed (12

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sah-0025
ENSSHAG00000001499.1
G3VES9
2
LLPS-Sah-0188
ENSSHAG00000012000.1
G3WF30
3
LLPS-Sah-3213
ENSSHAG00000009788.1
G3W7H6
4
LLPS-Sah-3652
ENSSHAG00000007586.1
G3W004
5
LLPS-Sah-2125
ENSSHAG00000009954.1
G3W829
HNRNPA1
6
LLPS-Sah-0252
ENSSHAG00000013312.1
G3WJL6
HNRNPD
7
LLPS-Sah-0775
ENSSHAG00000017109.1
G3WXL3
HNRNPK
8
LLPS-Sah-2092
ENSSHAG00000013169.1
G3WJ44
KHDRBS2
9
LLPS-Sah-0663
ENSSHAG00000007593.1
G3W011
MAK16
10
LLPS-Sah-0322
ENSSHAG00000015351.1
G3WRM7
NGDN
11
LLPS-Sah-2469
ENSSHAG00000017102.1
G3WXK6
TLE3
12
LLPS-Sah-1975
ENSSHAG00000002538.1
G3VI62
YTHDC1