Pan troglodytes      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pat-1802
ENSPTRG00000049417.1
A5A6H4
HNRNPA1
2
LLPS-Pat-0328
ENSPTRG00000016215.6
H2QPS6
HNRNPD
3
LLPS-Pat-0821
ENSPTRG00000048500.1
K7C562
HNRNPK
4
LLPS-Pat-0446
ENSPTRG00000010941.5
H2QG92
HNRNPL
5
LLPS-Pat-1043
ENSPTRG00000000469.7
H2PYJ6
KHDRBS1
6
LLPS-Pat-3933
ENSPTRG00000018311.4
H2QT91
KHDRBS2
7
LLPS-Pat-0546
ENSPTRG00000020608.6
H2QZY6
KHDRBS3
8
LLPS-Pat-2249
ENSPTRG00000016955.5
A0A2I3TMK9
LOC461829
9
LLPS-Pat-3401
ENSPTRG00000020149.5
H2QW04
MAK16
10
LLPS-Pat-0016
ENSPTRG00000006177.6
H2R2X6
NGDN
11
LLPS-Pat-4913
ENSPTRG00000052587.1
A5A6M3
RBMX
12
LLPS-Pat-2799
ENSPTRG00000007231.7
H2Q9Q1
TLE3
13
LLPS-Pat-3229
ENSPTRG00000016105.5
H2RA35
YTHDC1