Nomascus leucogenys      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nol-3152
ENSNLEG00000017659.2
G1S7F5
HNRNPA1
2
LLPS-Nol-1729
ENSNLEG00000008600.2
G1RBD3
HNRNPD
3
LLPS-Nol-0670
ENSNLEG00000003486.3
A0A2I3GEF5
HNRNPK
4
LLPS-Nol-1959
ENSNLEG00000014696.2
G1RXB1
HNRNPL
5
LLPS-Nol-0983
ENSNLEG00000002148.3
G1QNU0
KHDRBS1
6
LLPS-Nol-2890
ENSNLEG00000004454.2
A0A2I3G9J7
LOC100585728
7
LLPS-Nol-1579
ENSNLEG00000028118.1
A0A2I3GTD6
MAK16
8
LLPS-Nol-1674
ENSNLEG00000027739.1
A0A2I3GN57
NGDN
9
LLPS-Nol-1624
ENSNLEG00000002964.3
A0A2I3HU52
RBMX
10
LLPS-Nol-1731
ENSNLEG00000013552.3
A0A2I3GKB9
TLE3
11
LLPS-Nol-1230
ENSNLEG00000009202.3
G1RDC8
YTHDC1