Monodelphis domestica      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mod-0917
ENSMODG00000001436.2
F7BCE9
2
LLPS-Mod-3936
ENSMODG00000013418.4
F7CN94
3
LLPS-Mod-1541
ENSMODG00000011898.3
F7EH18
HNRNPD
4
LLPS-Mod-1177
ENSMODG00000008402.3
F7BUQ2
HNRNPK
5
LLPS-Mod-0593
ENSMODG00000017551.2
F7E0Y6
KHDRBS1
6
LLPS-Mod-1126
ENSMODG00000018714.2
F7FCC7
KHDRBS2
7
LLPS-Mod-0697
ENSMODG00000000975.2
F7ESF8
KHDRBS3
8
LLPS-Mod-1908
ENSMODG00000011096.3
F7DL52
MAK16
9
LLPS-Mod-0873
ENSMODG00000004257.3
F6TVY4
NGDN
10
LLPS-Mod-3063
ENSMODG00000009200.3
F7CCH6
TLE3
11
LLPS-Mod-2421
ENSMODG00000020754.3
F6RD50
YTHDC1