Carlito syrichta      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cas-0900
ENSTSYG00000012949.2
A0A1U7TFG5
HNRNPA1
2
LLPS-Cas-3428
ENSTSYG00000010395.2
A0A1U7T6B9
HNRNPD
3
LLPS-Cas-0779
ENSTSYG00000001196.2
A0A1U7SY96
HNRNPK
4
LLPS-Cas-0024
ENSTSYG00000012058.2
A0A1U7UJP8
LOC103270354
5
LLPS-Cas-0184
ENSTSYG00000028100.1
A0A1U7TXM7
MAK16
6
LLPS-Cas-0822
ENSTSYG00000009606.3
A0A1U7UKY8
NGDN
7
LLPS-Cas-1854
ENSTSYG00000009555.2
A0A1U7UE35
RBMX
8
LLPS-Cas-3566
ENSTSYG00000002515.2
A0A1U7UL72
TLE3
9
LLPS-Cas-3125
ENSTSYG00000011668.2
A0A1U7U0J0
YTHDC1