Aotus nancymaae      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 13 genes.  Reviewed (0 or Unreviewed (13

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aon-0019
ENSANAG00000032133.1
A0A2K5E651
2
LLPS-Aon-1452
ENSANAG00000038150.1
A0A2K5F8H2
3
LLPS-Aon-2092
ENSANAG00000023645.1
A0A2K5CRR6
4
LLPS-Aon-3503
ENSANAG00000035221.1
A0A2K5EQM8
HNRNPD
5
LLPS-Aon-3252
ENSANAG00000030728.1
A0A2K5E076
HNRNPK
6
LLPS-Aon-1372
ENSANAG00000026939.1
A0A2K5DB53
KHDRBS1
7
LLPS-Aon-1563
ENSANAG00000024792.1
A0A2K5CYK1
KHDRBS2
8
LLPS-Aon-0635
ENSANAG00000019406.1
A0A2K5C341
KHDRBS3
9
LLPS-Aon-0417
ENSANAG00000030954.1
A0A2K5DZQ2
MAK16
10
LLPS-Aon-0165
ENSANAG00000037066.1
A0A2K5F1H6
NGDN
11
LLPS-Aon-3934
ENSANAG00000028304.1
A0A2K5DJS5
RBMX
12
LLPS-Aon-3621
ENSANAG00000030943.1
A0A2K5E4H6
TLE3
13
LLPS-Aon-1991
ENSANAG00000001522.1
A0A2K5BV64
YTHDC1