Anolis carolinensis      Sam68 nuclear body


※ Sam68 nuclear body introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Sam68 nuclear bodies (SNBs) is a kind of these bodies located in Nucleus, Its component of Nucleic acids or RNPs are Chloroplast-specific mRNAs Long non-coding RNA, and it is related to mRNAs trafficking through the nucleus (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID:27838525


There are 11 genes.  Reviewed (0 or Unreviewed (11

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anc-1693
ENSACAG00000001479.2
G1K9R8
HNRNPK
2
LLPS-Anc-3248
ENSACAG00000009810.3
H9GFQ7
hnrnpl
3
LLPS-Anc-0012
ENSACAG00000011693.3
H9GI32
KHDRBS1
4
LLPS-Anc-1448
ENSACAG00000006691.3
G1KFP6
KHDRBS2
5
LLPS-Anc-2073
ENSACAG00000012042.3
G1KLV1
KHDRBS3
6
LLPS-Anc-3538
ENSACAG00000010017.3
G1KJN6
LOC100553231
7
LLPS-Anc-1422
ENSACAG00000000888.3
H9G4C6
MAK16
8
LLPS-Anc-2025
ENSACAG00000007340.3
H9GCL2
NGDN
9
LLPS-Anc-2031
ENSACAG00000009551.3
H9GFE5
rbmx
10
LLPS-Anc-3765
ENSACAG00000014467.3
H9GLM6
TLE3
11
LLPS-Anc-1628
ENSACAG00000009697.3
G1KJB2
YTHDC1