Anolis carolinensis      Receptor cluster


※ Receptor cluster introduction

    One of the most actively studied areas in which spatial heterogeneity is emerging as a key factor is signal transduction at the cell membrane. In addition to imposing a quasi-two-dimensional geometry, the membrane plays host to a large diversity of cellular components, and interactions among these components give rise to a complex spatial organization. A central theme of recent work in this field is the prevalence and role of membrane clusters, groups of colocalized molecules that often participate in the detection of external signals and subsequently drive responses within the cell (1).

Reference
1. Mugler A., et al (2012) Membrane Clustering and the Role of Rebinding in Biochemical Signaling. Biophys J, 102(5): 1069–1078. PMID: 22404929


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Anc-2748
ENSACAG00000006634.3
H9GBP9
2
LLPS-Anc-0921
ENSACAG00000007652.3
G1KHB2
CFTR
3
LLPS-Anc-3144
ENSACAG00000003690.3
H9G851
ITK
4
LLPS-Anc-3233
ENSACAG00000017514.3
G1KU23
PDE3A
5
LLPS-Anc-0574
ENSACAG00000014408.3
R4GAZ8
SLC2A4
6
LLPS-Anc-3147
ENSACAG00000001920.3
G1KA11
SNAP25
7
LLPS-Anc-1081
ENSACAG00000000768.3
G1K8U5
SYK