Ficedula albicollis      Neuronal granule


※ Neuronal granule introduction

    Neuronal granules are also referred to as neuronal transport granules, RNA-transporting granules, neuronal RNA granules, dendritic P-body like structures (dlP-bodies), FMRP granules and Staufen granules(1,2). They are broadly identified by the presence of two highly conserved proteins: Staufen, a double-stranded RNA-binding protein and FMRP. As a kind of cytoplasmic RNP bodies located in Cytoplasm of neurons, neuronal transport RNPs have highly specialized functions and have been shown to interact or co-localize with components of GW/P bodies (1), it's microtubule-dependent and contain Silenced mRNAs and ribosomes components. Neuronal RNA bodies is of spherical shape with fluid characteristics, proved to be associated with rotein synthesis in response to exogenous stimuli (2).

Reference
1. Moser, J. J., & Fritzler, M. J. (2013) Relationship of other cytoplasmic ribonucleoprotein bodies (cRNPB) to GW/P bodies. Adv Exp Med Biol, 768, 213-242. PMID: 23224973
2. Hirano, M., Muto, M., Sakai, M., Kondo, H., Kobayashi, S., Kariwa, H., Yoshii, K.(2017) Dendritic transport of tick-borne flavivirus RNA by neuronal granules affects development of neurological disease. Proc Natl Acad Sci U S A, 114, 9960–9965. PMID: 28847946
3. Darling, A. L., Liu, Y., Oldfield, C. J., & Uversky, V. N. (2018) Intrinsically Disordered Proteome of Human Membrane-Less Organelles. Proteomics, 18(5-6), e1700193. PMID: 27838525


There are 37 genes.  Reviewed (0 or Unreviewed (37

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Fia-0134
ENSFALG00000001530.1
U3JFN7
2
LLPS-Fia-0820
ENSFALG00000007592.1
U3JYT3
3
LLPS-Fia-2324
ENSFALG00000011923.1
U3KBP1
4
LLPS-Fia-0847
ENSFALG00000001291.1
U3JF05
CAPRIN1
5
LLPS-Fia-3564
ENSFALG00000008809.1
U3K2D3
CPEB4
6
LLPS-Fia-0302
ENSFALG00000008696.1
U3K215
DDX1
7
LLPS-Fia-1070
ENSFALG00000002317.1
U3JI17
DDX5
8
LLPS-Fia-0680
ENSFALG00000007069.1
U3JX71
EEF1A1
9
LLPS-Fia-2096
ENSFALG00000005241.1
U3JRR6
EIF2A
10
LLPS-Fia-0114
ENSFALG00000005244.1
U3JRR3
EIF2S1
11
LLPS-Fia-0621
ENSFALG00000010608.1
U3K7R6
EIF2S2
12
LLPS-Fia-1278
ENSFALG00000006190.1
U3JUK8
EIF4E
13
LLPS-Fia-1134
ENSFALG00000005331.1
U3JS07
ELAVL4
14
LLPS-Fia-2970
ENSFALG00000007089.1
U3JX95
EWSR1
15
LLPS-Fia-0578
ENSFALG00000012085.1
U3KC61
FMR1
16
LLPS-Fia-0785
ENSFALG00000008301.1
U3K0U7
FXR1
17
LLPS-Fia-1395
ENSFALG00000008253.1
U3K0Q2
G3BP1
18
LLPS-Fia-3688
ENSFALG00000014395.1
U3KJ07
HNRNPA0
19
LLPS-Fia-0006
ENSFALG00000009527.1
U3K4H6
HNRNPA2B1
20
LLPS-Fia-2328
ENSFALG00000007654.1
U3JYY0
HNRNPAB
21
LLPS-Fia-1215
ENSFALG00000005716.1
U3JT61
HNRNPD
22
LLPS-Fia-1997
ENSFALG00000011528.1
U3KAI8
HNRNPU
23
LLPS-Fia-1755
ENSFALG00000011765.1
U3KB77
NONO
24
LLPS-Fia-a059
ENSFALG00000007291.1
U3JXW6
PSD
25
LLPS-Fia-0665
ENSFALG00000008750.1
U3K275
PSPC1
26
LLPS-Fia-0714
ENSFALG00000015025.1
U3KKT6
PURA
27
LLPS-Fia-1396
ENSFALG00000002070.1
U3JH97
RIPK4
28
LLPS-Fia-1610
ENSFALG00000012365.1
U3KD18
RPL3
29
LLPS-Fia-2409
ENSFALG00000013334.1
U3KFW2
RTCB
30
LLPS-Fia-2122
ENSFALG00000001927.1
U3JGV8
RTRAF
31
LLPS-Fia-0035
ENSFALG00000000731.1
U3JDA0
SFPQ
32
LLPS-Fia-2505
ENSFALG00000000505.1
U3JCL7
SRSF10
33
LLPS-Fia-1434
ENSFALG00000012940.1
U3KEQ2
STAU1
34
LLPS-Fia-0130
ENSFALG00000008552.1
U3K1L3
STAU2
35
LLPS-Fia-0410
ENSFALG00000002895.1
U3JJR4
SYNCRIP
36
LLPS-Fia-3698
ENSFALG00000013072.1
U3KF39
TRIM2
37
LLPS-Fia-2861
ENSFALG00000008157.1
U3K0F1
TRIM3