Yarrowia lipolytica      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Yal-0759
YALI0_B06116g
Q6CFK6
MRPS9
2
LLPS-Yal-0297
YALI0_A12001g
Q6CH64
YALI0_A12001g
3
LLPS-Yal-1177
YALI0_B01386g
Q6CG28
YALI0_B01386g
4
LLPS-Yal-1179
YALI0_F15147g
Q6C1L7
YALI0_F15147g
5
LLPS-Yal-1206
YALI0_F26433g
Q6C0A5
YALI0_F26433g
6
LLPS-Yal-1209
YALI0_F27995g
Q6C040
YALI0_F27995g