Puccinia graminis      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pug-0868
PGTG_02012
E3JWX6
PGTG_02012
2
LLPS-Pug-0930
PGTG_04643
E3K3N5
PGTG_04643
3
LLPS-Pug-0800
PGTG_07077
E3KAP9
PGTG_07077
4
LLPS-Pug-1087
PGTG_10360
E3KKR4
PGTG_10360
5
LLPS-Pug-1020
PGTG_17451
E3L589
PGTG_17451