Pelodiscus sinensis      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 34 genes.  Reviewed (0 or Unreviewed (34

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pes-0387
ENSPSIG00000005026.1
K7FBH8
2
LLPS-Pes-1137
ENSPSIG00000014261.1
K7G6R5
3
LLPS-Pes-1749
ENSPSIG00000008820.1
K7FP00
4
LLPS-Pes-2939
ENSPSIG00000011184.1
K7FWM8
5
LLPS-Pes-3287
ENSPSIG00000012778.1
K7G1U1
6
LLPS-Pes-1803
ENSPSIG00000018093.1
K7GJK0
AARS2
7
LLPS-Pes-2944
ENSPSIG00000016813.1
K7GFF0
DARS2
8
LLPS-Pes-3742
ENSPSIG00000001127.1
K7EZB4
DDX28
9
LLPS-Pes-3221
ENSPSIG00000007018.1
K7FI46
ERAL1
10
LLPS-Pes-2161
ENSPSIG00000002245.1
K7F2J9
FASTKD1
11
LLPS-Pes-1879
ENSPSIG00000017841.1
K7GIN2
FASTKD2
12
LLPS-Pes-1897
ENSPSIG00000005703.1
K7FDN6
FASTKD5
13
LLPS-Pes-1770
ENSPSIG00000017285.1
K7GGS9
MCU
14
LLPS-Pes-3435
ENSPSIG00000017622.1
K7GHW8
MRM1
15
LLPS-Pes-2190
ENSPSIG00000013706.1
K7G4Y8
MRPL19
16
LLPS-Pes-2108
ENSPSIG00000011117.1
K7FWB9
MRPL43
17
LLPS-Pes-0344
ENSPSIG00000011536.1
K7FXQ5
MRPL47
18
LLPS-Pes-2779
ENSPSIG00000014565.1
K7G7Y4
MRPS27
19
LLPS-Pes-0209
ENSPSIG00000004039.1
K7F8D0
MRPS31
20
LLPS-Pes-0667
ENSPSIG00000008421.1
K7FMM4
MRPS7
21
LLPS-Pes-1164
ENSPSIG00000015761.1
K7GBQ9
MRPS9
22
LLPS-Pes-2849
ENSPSIG00000015809.1
K7GC07
MTPAP
23
LLPS-Pes-2769
ENSPSIG00000013873.1
K7G5K4
NLRX1
24
LLPS-Pes-1563
ENSPSIG00000002984.1
K7F4Z0
NOA1
25
LLPS-Pes-1416
ENSPSIG00000012190.1
K7FZV5
PMPCB
26
LLPS-Pes-1946
ENSPSIG00000013120.1
K7G3K9
PNPT1
27
LLPS-Pes-0780
ENSPSIG00000014559.1
K7G7R0
PTCD2
28
LLPS-Pes-1317
ENSPSIG00000013610.1
K7G4X8
SUCLG2
29
LLPS-Pes-2658
ENSPSIG00000017997.1
K7GJ80
SUPV3L1
30
LLPS-Pes-1413
ENSPSIG00000006643.1
K7FGX5
TFB1M
31
LLPS-Pes-1209
ENSPSIG00000004052.1
K7F8E4
TRMT10C
32
LLPS-Pes-3352
ENSPSIG00000015701.1
K7GBK9
TRUB2
33
LLPS-Pes-2380
ENSPSIG00000007001.1
K7FHZ9
TWNK
34
LLPS-Pes-0943
ENSPSIG00000009854.1
K7FS56
YME1L1