Oryctolagus cuniculus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 41 genes.  Reviewed (0 or Unreviewed (41

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orc-0368
ENSOCUG00000010584.3
G1SZL6
2
LLPS-Orc-0721
ENSOCUG00000021467.2
G1TFY8
3
LLPS-Orc-1791
ENSOCUG00000023749.2
G1U2F6
4
LLPS-Orc-0009
ENSOCUG00000021422.2
G1TSK4
AARS2
5
LLPS-Orc-2789
ENSOCUG00000007841.3
G1STX8
DARS2
6
LLPS-Orc-1058
ENSOCUG00000023074.1
G1TUL5
DDX28
7
LLPS-Orc-3011
ENSOCUG00000006515.2
G1SR61
DHX30
8
LLPS-Orc-4377
ENSOCUG00000005572.2
G1SP85
ERAL1
9
LLPS-Orc-3913
ENSOCUG00000023964.1
G1THT1
FASTK
10
LLPS-Orc-3503
ENSOCUG00000002198.3
G1SH16
FASTKD1
11
LLPS-Orc-1671
ENSOCUG00000010515.2
G1SZG4
FASTKD2
12
LLPS-Orc-1943
ENSOCUG00000008867.3
G1SW17
FASTKD5
13
LLPS-Orc-4199
ENSOCUG00000010029.3
G1SYE7
GRSF1
14
LLPS-Orc-2281
ENSOCUG00000017937.3
G1TES6
HSD17B10
15
LLPS-Orc-3465
ENSOCUG00000016663.2
G1TS30
KIAA0391
16
LLPS-Orc-1170
ENSOCUG00000014855.3
G1T890
MCU
17
LLPS-Orc-3822
ENSOCUG00000012433.3
G1T3A6
ME2
18
LLPS-Orc-3554
ENSOCUG00000012149.2
G1TF30
MRM1
19
LLPS-Orc-1135
ENSOCUG00000002219.2
G1SH27
MRM3
20
LLPS-Orc-0688
ENSOCUG00000001712.3
G1SFZ2
MRPL19
21
LLPS-Orc-3849
ENSOCUG00000002742.3
G1SI76
MRPL43
22
LLPS-Orc-0251
ENSOCUG00000017886.3
G1TEN4
MRPL47
23
LLPS-Orc-4100
ENSOCUG00000007961.3
G1SU61
MRPS27
24
LLPS-Orc-1520
ENSOCUG00000017928.2
G1TMZ2
MRPS7
25
LLPS-Orc-2801
ENSOCUG00000015017.3
G1T8K1
MRPS9
26
LLPS-Orc-1128
ENSOCUG00000004276.2
G1SLF7
MTERF3
27
LLPS-Orc-0789
ENSOCUG00000007276.3
G1SSQ3
MTPAP
28
LLPS-Orc-2446
ENSOCUG00000024892.2
G1TY83
NLRX1
29
LLPS-Orc-0098
ENSOCUG00000016330.3
G1TBF5
NOA1
30
LLPS-Orc-1029
ENSOCUG00000010200.3
G1SYT7
PMPCB
31
LLPS-Orc-4352
ENSOCUG00000006889.2
G1SRY1
PNPT1
32
LLPS-Orc-4164
ENSOCUG00000007970.3
G1TX58
PTCD2
33
LLPS-Orc-3995
ENSOCUG00000027885.1
G1TXL6
RPUSD3
34
LLPS-Orc-4326
ENSOCUG00000017039.2
G1TMK5
RPUSD4
35
LLPS-Orc-3988
ENSOCUG00000012376.3
G1T361
SUCLG2
36
LLPS-Orc-4130
ENSOCUG00000004933.3
G1SMU4
SUPV3L1
37
LLPS-Orc-2781
ENSOCUG00000012154.2
G1T2Q1
TFB1M
38
LLPS-Orc-2760
ENSOCUG00000011103.3
G1T0M2
TRMT10C
39
LLPS-Orc-2921
ENSOCUG00000026296.2
G1TLR9
TRUB2
40
LLPS-Orc-0868
ENSOCUG00000002746.3
G1SI82
TWNK
41
LLPS-Orc-2223
ENSOCUG00000011293.3
G1T116
YME1L1