Neosartorya fischeri      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 9 genes.  Reviewed (0 or Unreviewed (9

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nef-0525
NFIA_086430
A1DH31
mrpl4
2
LLPS-Nef-0403
NFIA_045340
A1CVD8
NFIA_045340
3
LLPS-Nef-0450
NFIA_051090
A1DLU3
NFIA_051090
4
LLPS-Nef-1355
NFIA_073570
A1DDI4
NFIA_073570
5
LLPS-Nef-0565
NFIA_076410
A1DEA4
NFIA_076410
6
LLPS-Nef-0545
NFIA_090840
A1DIB9
NFIA_090840
7
LLPS-Nef-0572
NFIA_102910
A1CW04
NFIA_102910
8
LLPS-Nef-1214
NFIA_104670
A1CWH7
NFIA_104670
9
LLPS-Nef-0542
NFIA_107830
A1CXD9
NFIA_107830