※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Mod-0901	ENSMODG00000012822.3	F7DD82
2		LLPS-Mod-4186	ENSMODG00000011975.3	F7B9Y3
3		LLPS-Mod-3825	ENSMODG00000018926.2	F7GJV5	AARS2
4		LLPS-Mod-3207	ENSMODG00000004188.3	F6Y9Y7	DARS2
5		LLPS-Mod-4330	ENSMODG00000005303.2	F7DMJ8	DDX28
6		LLPS-Mod-1768	ENSMODG00000014285.3	F6WKE0	DHX30
7		LLPS-Mod-1691	ENSMODG00000019305.3	F6RYG3	ERAL1
8		LLPS-Mod-3259	ENSMODG00000008073.3	F6YJQ6	FASTKD1
9		LLPS-Mod-3817	ENSMODG00000015997.3	F7EZ09	FASTKD2
10		LLPS-Mod-0388	ENSMODG00000019088.3	F7FNC0	GRSF1
11		LLPS-Mod-2246	ENSMODG00000020889.2	H9H7Q1	HSD17B10
12		LLPS-Mod-1750	ENSMODG00000000088.3	F6Q901	MCU
13		LLPS-Mod-2487	ENSMODG00000010968.3	F7BC34	ME2
14		LLPS-Mod-3195	ENSMODG00000003307.2	F7DZ27	MRM1
15		LLPS-Mod-3698	ENSMODG00000010029.3	F6TUK5	MRM3
16		LLPS-Mod-1606	ENSMODG00000007969.3	F7DQT5	MRPL19
17		LLPS-Mod-1671	ENSMODG00000021301.3	F7G3T0	MRPL47
18		LLPS-Mod-3608	ENSMODG00000001687.3	F6S7T5	MRPS27
19		LLPS-Mod-2214	ENSMODG00000010347.3	F6S8D0	MRPS31
20		LLPS-Mod-0533	ENSMODG00000007290.3	F7FCF7	MRPS7
21		LLPS-Mod-1497	ENSMODG00000002479.3	F7BVW6	MRPS9
22		LLPS-Mod-4037	ENSMODG00000006966.3	F6QV92	MTERF3
23		LLPS-Mod-2733	ENSMODG00000007924.3	F7GIA7	MTPAP
24		LLPS-Mod-0768	ENSMODG00000013249.3	F7DUM2	NLRX1
25		LLPS-Mod-1812	ENSMODG00000020703.3	F7D1E1	NOA1
26		LLPS-Mod-2302	ENSMODG00000017224.3	F6WXQ5	PMPCB
27		LLPS-Mod-4310	ENSMODG00000001984.2	F6RID9	PNPT1
28		LLPS-Mod-2071	ENSMODG00000006478.3	F7FG73	POLRMT
29		LLPS-Mod-2621	ENSMODG00000001350.3	F7FW99	PTCD1
30		LLPS-Mod-2518	ENSMODG00000001695.2	F6S7F6	PTCD2
31		LLPS-Mod-2735	ENSMODG00000005210.2	F7A209	RPUSD3
32		LLPS-Mod-3810	ENSMODG00000004521.2	F6UR33	RPUSD4
33		LLPS-Mod-3573	ENSMODG00000003294.3	F7EG06	SUCLG2
34		LLPS-Mod-3625	ENSMODG00000010700.3	H9H6E6	SUPV3L1
35		LLPS-Mod-3443	ENSMODG00000008169.3	F7EKY1	TFB1M
36		LLPS-Mod-4067	ENSMODG00000025175.2	F7FXF7	TRMT10C
37		LLPS-Mod-3807	ENSMODG00000005940.2	F6WW62	TRUB2
38		LLPS-Mod-4315	ENSMODG00000011966.2	F7CUW8	TWNK
39		LLPS-Mod-2889	ENSMODG00000008389.3	F7BVC8	YME1L1