Melampsora laricipopulina      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 5 genes.  Reviewed (0 or Unreviewed (5

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mel-0989
MELLADRAFT_123249
F4RZY4
MELLADRAFT_123249
2
LLPS-Mel-0177
MELLADRAFT_32543
F4R3E9
MELLADRAFT_32543
3
LLPS-Mel-0860
MELLADRAFT_50335
F4S3X3
MELLADRAFT_50335
4
LLPS-Mel-0283
MELLADRAFT_51479
F4R5A6
MELLADRAFT_51479
5
LLPS-Mel-1162
MELLADRAFT_94488
F4RBL4
MELLADRAFT_94488