Ictidomys tridecemlineatus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 41 genes.  Reviewed (0 or Unreviewed (41

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ict-2566
ENSSTOG00000013499.3
I3ML53
AARS2
2
LLPS-Ict-0212
ENSSTOG00000015250.3
I3MPF8
DARS2
3
LLPS-Ict-2286
ENSSTOG00000002064.3
I3MZC2
DDX28
4
LLPS-Ict-3716
ENSSTOG00000022367.2
A0A287D7V0
DHX30
5
LLPS-Ict-3512
ENSSTOG00000003459.3
I3M2C3
ERAL1
6
LLPS-Ict-3564
ENSSTOG00000016075.3
I3MQV6
FASTK
7
LLPS-Ict-0883
ENSSTOG00000011651.3
I3MHR3
FASTKD1
8
LLPS-Ict-2192
ENSSTOG00000022821.2
I3N9Z6
FASTKD2
9
LLPS-Ict-4593
ENSSTOG00000011569.3
I3MHK6
GRSF1
10
LLPS-Ict-0513
ENSSTOG00000005535.3
I3M679
HSD17B10
11
LLPS-Ict-3020
ENSSTOG00000011766.3
I3MHY6
Kiaa0391
12
LLPS-Ict-4592
ENSSTOG00000028416.2
A0A287CU33
MCU
13
LLPS-Ict-1378
ENSSTOG00000027218.2
I3N8Z1
ME2
14
LLPS-Ict-4706
ENSSTOG00000002422.3
I3M0E5
MRM1
15
LLPS-Ict-2997
ENSSTOG00000015460.3
I3MPS5
MRM2
16
LLPS-Ict-4640
ENSSTOG00000016426.3
I3MRI3
MRM3
17
LLPS-Ict-1227
ENSSTOG00000002873.3
I3M196
MRPL19
18
LLPS-Ict-3001
ENSSTOG00000009016.3
I3MCR7
MRPL43
19
LLPS-Ict-3653
ENSSTOG00000032487.1
A0A287D3B3
MRPL47
20
LLPS-Ict-3477
ENSSTOG00000006565.3
I3M863
MRPS27
21
LLPS-Ict-1703
ENSSTOG00000000986.3
I3LXQ8
MRPS31
22
LLPS-Ict-1302
ENSSTOG00000015200.3
I3MPB8
MRPS7
23
LLPS-Ict-0771
ENSSTOG00000016370.3
I3MRF3
MRPS9
24
LLPS-Ict-2723
ENSSTOG00000008021.3
I3MAV2
MTERF3
25
LLPS-Ict-0662
ENSSTOG00000000734.3
I3LX89
MTPAP
26
LLPS-Ict-3522
ENSSTOG00000014477.3
A0A287D9H1
NLRX1
27
LLPS-Ict-4326
ENSSTOG00000003793.3
I3M301
NOA1
28
LLPS-Ict-0975
ENSSTOG00000005143.3
I3M5K7
PMPCB
29
LLPS-Ict-3935
ENSSTOG00000006304.3
I3N887
PNPT1
30
LLPS-Ict-1399
ENSSTOG00000003431.3
I3M2A6
POLRMT
31
LLPS-Ict-2129
ENSSTOG00000001682.3
I3LZ19
Ptcd1
32
LLPS-Ict-0983
ENSSTOG00000006596.3
I3M875
PTCD2
33
LLPS-Ict-3374
ENSSTOG00000002125.3
I3LZT3
RPUSD3
34
LLPS-Ict-4113
ENSSTOG00000025280.2
I3N0H8
RPUSD4
35
LLPS-Ict-4345
ENSSTOG00000020195.2
I3MUN3
SUCLG2
36
LLPS-Ict-1127
ENSSTOG00000000503.3
I3LWS4
SUPV3L1
37
LLPS-Ict-3942
ENSSTOG00000026264.2
I3N709
TFB1M
38
LLPS-Ict-3125
ENSSTOG00000012199.3
I3N6R9
TRMT10C
39
LLPS-Ict-1529
ENSSTOG00000008024.3
I3MAV5
Trub2
40
LLPS-Ict-4444
ENSSTOG00000009030.3
I3MCS7
TWNK
41
LLPS-Ict-0493
ENSSTOG00000027471.2
I3N3N6
YME1L1