Erinaceus europaeus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 10 genes.  Reviewed (0 or Unreviewed (10

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Ere-0312
ENSEEUG00000005017.1
A0A1S2ZDR5
DDX28
2
LLPS-Ere-0259
ENSEEUG00000005080.1
A0A1S3A844
HSD17B10
3
LLPS-Ere-0256
ENSEEUG00000009125.1
A0A1S3A719
LOC103119943
4
LLPS-Ere-0276
ENSEEUG00000013434.1
A0A1S3W3K4
MRM1
5
LLPS-Ere-1072
ENSEEUG00000004807.1
A0A1S3A6W3
MRPL43
6
LLPS-Ere-0531
ENSEEUG00000015775.1
A0A1S2ZUT6
MRPS7
7
LLPS-Ere-0992
ENSEEUG00000014031.1
A0A1S3A979
PTCD2
8
LLPS-Ere-0980
ENSEEUG00000014899.1
A0A1S2ZBC1
TFB1M
9
LLPS-Ere-0561
ENSEEUG00000004696.1
A0A1S3AC61
TRMT10C
10
LLPS-Ere-0677
ENSEEUG00000008908.1
A0A1S2ZZ37
TRUB2