Drosophila melanogaster      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 29 genes.  Reviewed (0 or Unreviewed (29

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Drm-1668
FBgn0051739
Q9VJH2
AspRS-m
2
LLPS-Drm-0879
FBgn0038737
Q9VDT6
CG11447
3
LLPS-Drm-1878
FBgn0036889
Q9VW14
CG14100
4
LLPS-Drm-1067
FBgn0086130
Q9VPT3
Dbp21E2
5
LLPS-Drm-2369
FBgn0034307
Q8SZ15
DmelCG10914
6
LLPS-Drm-0672
FBgn0030217
Q9W2T3
DmelCG2124
7
LLPS-Drm-1731
FBgn0051643
Q960W0
DmelCG31643
8
LLPS-Drm-0520
FBgn0035591
Q9VRJ7
DmelCG4611
9
LLPS-Drm-2250
FBgn0038106
Q9VG07
DmelCG7488
10
LLPS-Drm-0328
FBgn0033060
Q29QN4
DmelCG7849
11
LLPS-Drm-0701
FBgn0042185
Q8IQ70
MCU
12
LLPS-Drm-1050
FBgn0029858
Q9W413
mldr
13
LLPS-Drm-2174
FBgn0037608
Q9VHN6
mRpL19
14
LLPS-Drm-2060
FBgn0034893
Q9W1L1
mRpL43
15
LLPS-Drm-1334
FBgn0014023
Q8T3V6
mRpL47
16
LLPS-Drm-0415
FBgn0036557
Q9VUX1
mRpS31
17
LLPS-Drm-0185
FBgn0032236
Q9VKX4
mRpS7
18
LLPS-Drm-0740
FBgn0037529
Q8SXF0
mRpS9
19
LLPS-Drm-0694
FBgn0032154
Q9VL76
mtDNA-helicase
20
LLPS-Drm-1247
FBgn0037008
Q9VPD5
mTerf3
21
LLPS-Drm-1530
FBgn0024360
O46102
MTPAP
22
LLPS-Drm-0948
FBgn0261938
Q9VPW4
mtRNApol
23
LLPS-Drm-2162
FBgn0261381
Q9VTM5
mtTFB1
24
LLPS-Drm-1842
FBgn0039846
Q9V9X7
PNPase
25
LLPS-Drm-0441
FBgn0029118
Q9V470
ScsbetaG
26
LLPS-Drm-1494
FBgn0021765
O18404
scu
27
LLPS-Drm-2227
FBgn0037232
Q9VN03
Suv3
28
LLPS-Drm-2092
FBgn0034351
Q7JUX9
trmt10c
29
LLPS-Drm-1869
FBgn0034792
F3YDF1
YME1L