Danio rerio      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Dar-2299
ENSDARG00000071240.6
A0A2R8QSU7
AARS
2
LLPS-Dar-0589
ENSDARG00000060861.8
E9QFP3
dars2
3
LLPS-Dar-1963
ENSDARG00000060411.6
A0A2R8RPB8
ddx28
4
LLPS-Dar-0843
ENSDARG00000077839.5
E7FCG0
dhx30
5
LLPS-Dar-2693
ENSDARG00000059887.6
B0S6U7
eral1
6
LLPS-Dar-2496
ENSDARG00000077075.5
B0S618
fastk
7
LLPS-Dar-3383
ENSDARG00000056128.7
E7F8W7
fastkd1
8
LLPS-Dar-2067
ENSDARG00000074031.5
F1RE69
fastkd2
9
LLPS-Dar-3003
ENSDARG00000053021.9
F8W4V6
grsf1
10
LLPS-Dar-3092
ENSDARG00000017781.6
Q5XJS8
hsd17b10
11
LLPS-Dar-1453
ENSDARG00000101175.2
Q08BI9
mcu
12
LLPS-Dar-2827
ENSDARG00000100718.2
A5PN55
me2
13
LLPS-Dar-3286
ENSDARG00000059658.6
F1QG96
mrm1
14
LLPS-Dar-1183
ENSDARG00000075368.5
X1WFE4
mrm2
15
LLPS-Dar-0433
ENSDARG00000011885.8
Q6DC47
mrpl19
16
LLPS-Dar-1902
ENSDARG00000076334.4
Q6DH43
mrpl43
17
LLPS-Dar-1838
ENSDARG00000075743.4
E7F6A5
mrpl47
18
LLPS-Dar-3336
ENSDARG00000059234.6
F1RDR2
mrps27
19
LLPS-Dar-0292
ENSDARG00000110763.1
A0A2R8QFH1
mrps31
20
LLPS-Dar-3888
ENSDARG00000101622.2
Q498Z6
mrps7
21
LLPS-Dar-2470
ENSDARG00000061505.6
F1QP17
mrps9
22
LLPS-Dar-1934
ENSDARG00000003207.8
Q1L8H2
mterf3
23
LLPS-Dar-0344
ENSDARG00000076155.4
E7FEW2
mtpap
24
LLPS-Dar-3714
ENSDARG00000073724.5
E7FDW7
nlrx1
25
LLPS-Dar-0255
ENSDARG00000102934.2
A9JRX9
noa1
26
LLPS-Dar-0445
ENSDARG00000016979.8
Q1L8E2
pmpcb
27
LLPS-Dar-1137
ENSDARG00000101220.2
A0A0R4ILV6
polrmt
28
LLPS-Dar-2681
ENSDARG00000076176.4
E7F3M0
ptcd1
29
LLPS-Dar-1795
ENSDARG00000035391.7
Q566X6
ptcd2
30
LLPS-Dar-3292
ENSDARG00000069082.5
A1L2E4
rnmtl1b
31
LLPS-Dar-2164
ENSDARG00000012674.9
Q6DBR0
rpusd4
32
LLPS-Dar-2613
ENSDARG00000075057.5
X1WBZ5
si:dkeyp-33b5.4
33
LLPS-Dar-1599
ENSDARG00000115585.1
F1R7X5
suclg2
34
LLPS-Dar-1586
ENSDARG00000077728.4
A4IG62
supv3l1
35
LLPS-Dar-0365
ENSDARG00000040727.8
A0A0R4IU10
tfb1m
36
LLPS-Dar-0770
ENSDARG00000041575.7
B8JM40
trmt10c
37
LLPS-Dar-3590
ENSDARG00000028379.8
F6P6I4
trub2
38
LLPS-Dar-4130
ENSDARG00000099900.2
A0A0R4ICC1
twnk
39
LLPS-Dar-2741
ENSDARG00000104401.2
A0A0R4IJC7
yme1l1b