Cyanidioschyzon merolae      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 14 genes.  Reviewed (0 or Unreviewed (14

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cym-0881
CME141C
M1UPK5
CYME_CME141C
2
LLPS-Cym-1158
CMH146C
M1VGK7
CYME_CMH146C
3
LLPS-Cym-0315
CMH261C
M1V520
CYME_CMH261C
4
LLPS-Cym-0740
CMI157C
M1VC43
CYME_CMI157C
5
LLPS-Cym-0106
CMJ257C
M1V872
CYME_CMJ257C
6
LLPS-Cym-0910
CMK087C
M1VCV1
CYME_CMK087C
7
LLPS-Cym-0474
CML156C
M1V5J1
CYME_CML156C
8
LLPS-Cym-0635
CMN201C
M1UU17
CYME_CMN201C
9
LLPS-Cym-0843
CMN222C
M1UU28
CYME_CMN222C
10
LLPS-Cym-0928
CMP140C
M1V645
CYME_CMP140C
11
LLPS-Cym-0205
CMQ175C
M1V6C4
CYME_CMQ175C
12
LLPS-Cym-0890
CMT452C
M1VII6
CYME_CMT452C
13
LLPS-Cym-0884
CMT485C
M1VCX2
CYME_CMT485C
14
LLPS-Cym-0906
CMT543C
M1V7W8
CYME_CMT543C