Cavia porcellus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 39 genes.  Reviewed (0 or Unreviewed (39

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Cap-3754
ENSCPOG00000004789.4
H0V3Y8
2
LLPS-Cap-4632
ENSCPOG00000009676.4
H0VF52
AARS2
3
LLPS-Cap-2628
ENSCPOG00000010575.4
H0VH72
DARS2
4
LLPS-Cap-4570
ENSCPOG00000013746.3
H0VPG1
DDX28
5
LLPS-Cap-0566
ENSCPOG00000000699.4
A0A286XAF3
DHX30
6
LLPS-Cap-3746
ENSCPOG00000009576.4
H0VEX6
ERAL1
7
LLPS-Cap-0248
ENSCPOG00000037276.1
A0A286XVU3
FASTK
8
LLPS-Cap-1847
ENSCPOG00000004972.4
H0V4D8
FASTKD1
9
LLPS-Cap-1200
ENSCPOG00000005624.4
H0V5X1
FASTKD2
10
LLPS-Cap-2160
ENSCPOG00000023356.2
H0W5V6
FASTKD5
11
LLPS-Cap-2682
ENSCPOG00000032944.1
A0A286XYY1
HSD17B10
12
LLPS-Cap-4654
ENSCPOG00000001780.4
H0UX11
LOC100713838
13
LLPS-Cap-4492
ENSCPOG00000015605.4
H0VTR4
MCU
14
LLPS-Cap-0406
ENSCPOG00000012583.4
A0A286XWT7
ME2
15
LLPS-Cap-2199
ENSCPOG00000004283.4
H0V2T2
MRM1
16
LLPS-Cap-0735
ENSCPOG00000020743.2
H0W385
MRM2
17
LLPS-Cap-2588
ENSCPOG00000026540.2
H0VZ28
MRM3
18
LLPS-Cap-2419
ENSCPOG00000024548.2
H0VUG4
MRPL19
19
LLPS-Cap-4381
ENSCPOG00000040768.1
A0A286XW56
MRPL43
20
LLPS-Cap-3428
ENSCPOG00000002312.4
H0UY95
Mrpl47
21
LLPS-Cap-2403
ENSCPOG00000040481.1
A0A286Y1Q9
MRPS27
22
LLPS-Cap-0917
ENSCPOG00000003332.4
H0V0M1
MRPS31
23
LLPS-Cap-2260
ENSCPOG00000001195.4
H0UVN6
MRPS7
24
LLPS-Cap-2360
ENSCPOG00000013967.4
H0VPY9
MRPS9
25
LLPS-Cap-4432
ENSCPOG00000003487.4
H0V0Z7
MTERF3
26
LLPS-Cap-0303
ENSCPOG00000004018.4
H0V274
MTPAP
27
LLPS-Cap-4144
ENSCPOG00000006501.4
A0A286XV96
NLRX1
28
LLPS-Cap-0128
ENSCPOG00000031454.1
A0A286XY83
NOA1
29
LLPS-Cap-0134
ENSCPOG00000008108.4
H0VBK8
PMPCB
30
LLPS-Cap-2156
ENSCPOG00000011008.4
H0VI82
PNPT1
31
LLPS-Cap-1062
ENSCPOG00000023061.2
H0VY05
POLRMT
32
LLPS-Cap-4645
ENSCPOG00000040168.1
A0A286XC84
PTCD2
33
LLPS-Cap-4386
ENSCPOG00000037956.1
A0A286XFF4
RPUSD3
34
LLPS-Cap-2462
ENSCPOG00000014971.4
H0VS98
RPUSD4
35
LLPS-Cap-2900
ENSCPOG00000013421.4
H0VNP8
SUCLG2
36
LLPS-Cap-3631
ENSCPOG00000010044.4
H0VG01
SUPV3L1
37
LLPS-Cap-3024
ENSCPOG00000030422.1
A0A286XY21
TFB1M
38
LLPS-Cap-2491
ENSCPOG00000013535.4
H0VNY6
TRUB2
39
LLPS-Cap-3202
ENSCPOG00000000950.4
H0UV35
TWNK