Aspergillus nidulans      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 8 genes.  Reviewed (0 or Unreviewed (8

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asn-0901
ANIA_01710
C8VNW0
ANIA_01710
2
LLPS-Asn-0888
ANIA_01957
Q5BBX3
ANIA_01957
3
LLPS-Asn-0584
ANIA_04723
C8VAV2
ANIA_04723
4
LLPS-Asn-1264
ANIA_05588
C8VG17
ANIA_05588
5
LLPS-Asn-0852
ANIA_06564
C8V0U7
ANIA_06564
6
LLPS-Asn-0443
ANIA_06904
Q5AXS6
ANIA_06904
7
LLPS-Asn-0278
ANIA_07609
Q5AVS1
ANIA_07609
8
LLPS-Asn-0201
ANIA_10940
C8VBA0
ANIA_10940