Aspergillus fumigatus      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Asfu-0851
AFUA_2G15610
Q4WZV7
AFUA_2G15610
2
LLPS-Asfu-0438
AFUA_4G08330
Q4WP80
AFUA_4G08330
3
LLPS-Asfu-0937
AFUA_4G11530
Q4WQ45
AFUA_4G11530
4
LLPS-Asfu-1297
AFUA_4G13450
Q4WQN6
AFUA_4G13450
5
LLPS-Asfu-1536
AFUA_5G10820
Q4WV50
AFUA_5G10820
6
LLPS-Asfu-1093
AFUA_5G13490
Q4WVV9
AFUA_5G13490
7
LLPS-Asfu-0398
AFUA_6G04560
Q4WDF4
AFUA_6G04560