Ailuropoda melanoleuca      Mitochondrial RNA granule


※ Mitochondrial RNA granule introduction

    Eukaryotic cells are inhomogeneously crowded with biological macromolecules (proteins and nucleic acids) and often contain numerous cellular bodies, including proteinaceous membrane-less organelles (PMLOs), They are formed as a result of highly regulated and reversible liquid-liquid demixing phase separation and represent condensed liquid droplets, which are invariantly enriched in intrinsically disordered proteins (1). Mitochondrial RNA granules is a kind of these bodies of spherical shape that located in mitochondria with mitochondrial mRNAs and mitochondrial ribosomes components and it’s proved to be related to the posttranscriptional RNA processing and biogenesis of mitochondrial ribosomes (1).

Reference
1. Uversky, V. N. (2017) Intrinsically disordered proteins in overcrowded milieu: Membrane-less organelles, phase separation, and intrinsic disorder. Curr Opin Struct Biol, 44, 18-30. PMID: 27838525


There are 41 genes.  Reviewed (0 or Unreviewed (41

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Aim-4390
ENSAMEG00000006224.1
G1LI23
2
LLPS-Aim-4037
ENSAMEG00000011742.1
G1LZ61
AARS2
3
LLPS-Aim-3400
ENSAMEG00000015617.1
G1MAW7
DARS2
4
LLPS-Aim-1685
ENSAMEG00000019426.1
G1MM92
DDX28
5
LLPS-Aim-0393
ENSAMEG00000013112.1
G1M3D1
DHX30
6
LLPS-Aim-3853
ENSAMEG00000004602.1
D2GU20
ERAL1
7
LLPS-Aim-3968
ENSAMEG00000013695.1
G1M526
FASTK
8
LLPS-Aim-0948
ENSAMEG00000010599.1
G1LVQ6
FASTKD1
9
LLPS-Aim-3642
ENSAMEG00000002917.1
G1L858
FASTKD2
10
LLPS-Aim-4094
ENSAMEG00000019478.1
G1MME0
FASTKD5
11
LLPS-Aim-1167
ENSAMEG00000005896.1
D2HC98
GRSF1
12
LLPS-Aim-2062
ENSAMEG00000005036.1
G1LEJ1
HSD17B10
13
LLPS-Aim-1721
ENSAMEG00000017050.1
G1MF85
MCU
14
LLPS-Aim-3899
ENSAMEG00000002933.1
D2H522
ME2
15
LLPS-Aim-2968
ENSAMEG00000008301.1
G1LNU9
MRM1
16
LLPS-Aim-1299
ENSAMEG00000003654.1
G1LAC3
MRM2
17
LLPS-Aim-0370
ENSAMEG00000008346.1
G1LP01
MRM3
18
LLPS-Aim-2850
ENSAMEG00000017428.1
G1MGD7
MRPL19
19
LLPS-Aim-2329
ENSAMEG00000017570.1
G1MGS7
MRPL43
20
LLPS-Aim-2382
ENSAMEG00000010876.1
G1LWJ2
MRPL47
21
LLPS-Aim-0851
ENSAMEG00000007215.1
D2HGU7
MRPS27
22
LLPS-Aim-1351
ENSAMEG00000011719.1
G1LZ09
MRPS31
23
LLPS-Aim-2296
ENSAMEG00000009287.1
G1LRU0
MRPS7
24
LLPS-Aim-1142
ENSAMEG00000013254.1
G1M3R2
MRPS9
25
LLPS-Aim-3574
ENSAMEG00000007290.1
D2HFX7
MTERF3
26
LLPS-Aim-0212
ENSAMEG00000017072.1
G1MFA7
MTPAP
27
LLPS-Aim-0050
ENSAMEG00000000031.1
G1KZI3
NLRX1
28
LLPS-Aim-2954
ENSAMEG00000008549.1
D2H8J1
NOA1
29
LLPS-Aim-3810
ENSAMEG00000015610.1
D2HKI2
PANDA_011891
30
LLPS-Aim-1980
ENSAMEG00000015309.1
G1MA07
PMPCB
31
LLPS-Aim-2569
ENSAMEG00000003772.1
G1LAW7
PNPT1
32
LLPS-Aim-0126
ENSAMEG00000002745.1
G1L7Q8
POLRMT
33
LLPS-Aim-4343
ENSAMEG00000007194.1
G1LKW3
PTCD2
34
LLPS-Aim-3935
ENSAMEG00000016227.1
D2HRA6
RPUSD3
35
LLPS-Aim-1003
ENSAMEG00000000127.1
D2HV09
RPUSD4
36
LLPS-Aim-3916
ENSAMEG00000017957.1
D2GXI0
SUPV3L1
37
LLPS-Aim-0671
ENSAMEG00000012761.1
G1M288
TFB1M
38
LLPS-Aim-1529
ENSAMEG00000019657.1
G1MMV4
TRMT10C
39
LLPS-Aim-1998
ENSAMEG00000015395.1
G1MA74
TRUB2
40
LLPS-Aim-1793
ENSAMEG00000017575.1
D2GXU0
TWNK
41
LLPS-Aim-2367
ENSAMEG00000001795.1
G1L4Y5
YME1L1