Pan paniscus      Microtubule


※ Microtubule introduction

    Microtubules (MTs) are tubulin heterodimers that are arranged in a parallel shape of hollow cylinders which play roles in regulating the mechanical structure and dynamics of cells. Much of the structure and dynamics of MTs is highly ordered (1). In fact, microtubules were enable to be used as platforms to understand the mechanisms underlying liquid–liquid phase separation, some RNA binding proteins on microtubules leads to the formation of mRNA-rich liquid-like compartments on microtubules (2).

Reference
1. Ilan, Y. (2019) Randomness in microtubule dynamics: an error that requires correction or an inherent plasticity required for normal cellular function? Cell Biol Int, PMID: 31042006
2. Maucuer, A., Desforges, B., Joshi, V., Boca, M., Kretov, D. A., Hamon, L., et al. (2018) Microtubules as platforms for probing liquid-liquid phase separation in cells - application to RNA-binding proteins. J Cell Sci, 131(11). PMID: 29728455


There are 4 genes.  Reviewed (0 or Unreviewed (4

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pap-2343
ENSPPAG00000005022.1
A0A2R8ZFZ1
MAPT
2
LLPS-Pap-0762
ENSPPAG00000043583.1
A0A2R9CJ30
POC1A
3
LLPS-Pap-3648
ENSPPAG00000030897.1
A0A2R9ADV2
POC1B
4
LLPS-Pap-1378
ENSPPAG00000011142.1
A0A2R8ZC21
TUBA4A