※ Microtubule introduction

    Microtubules (MTs) are tubulin heterodimers that are arranged in a parallel shape of hollow cylinders which play roles in regulating the mechanical structure and dynamics of cells. Much of the structure and dynamics of MTs is highly ordered (1). In fact, microtubules were enable to be used as platforms to understand the mechanisms underlying liquid–liquid phase separation, some RNA binding proteins on microtubules leads to the formation of mRNA-rich liquid-like compartments on microtubules (2).

Reference
1. Ilan, Y. (2019) Randomness in microtubule dynamics: an error that requires correction or an inherent plasticity required for normal cellular function? Cell Biol Int, PMID: 31042006
2. Maucuer, A., Desforges, B., Joshi, V., Boca, M., Kretov, D. A., Hamon, L., et al. (2018) Microtubules as platforms for probing liquid-liquid phase separation in cells - application to RNA-binding proteins. J Cell Sci, 131(11). PMID: 29728455

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No.	Status	DrLLPS ID	Ensemble Gene ID	UniProt Accession	Gene Name
1		LLPS-Lac-3861	ENSLACG00000007829.2	H3AGU3	LOC102347483
2		LLPS-Lac-2340	ENSLACG00000014454.1	H3B3D6	MAPT
3		LLPS-Lac-3453	ENSLACG00000018788.2	M3XL86	POC1A
4		LLPS-Lac-3592	ENSLACG00000003118.1	H3A1H5	POC1B