Xiphophorus maculatus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Xim-0078
ENSXMAG00000022466.1
A0A3B5QAD4
2
LLPS-Xim-0192
ENSXMAG00000019963.2
M4AZW5
3
LLPS-Xim-0258
ENSXMAG00000014426.2
M4AJ02
4
LLPS-Xim-0646
ENSXMAG00000007573.2
M3ZZF4
5
LLPS-Xim-1164
ENSXMAG00000005737.2
M3ZUA6
6
LLPS-Xim-1208
ENSXMAG00000004938.2
M3ZRX1
7
LLPS-Xim-1729
ENSXMAG00000005798.2
M3ZUF3
8
LLPS-Xim-1753
ENSXMAG00000017048.2
M4ARN3
9
LLPS-Xim-1954
ENSXMAG00000009282.2
A0A3B5QA15
10
LLPS-Xim-2123
ENSXMAG00000008238.2
M4A1B0
11
LLPS-Xim-2290
ENSXMAG00000005943.2
M3ZUS5
12
LLPS-Xim-2306
ENSXMAG00000024670.1
A0A3B5R4T8
13
LLPS-Xim-2589
ENSXMAG00000017620.2
M4AT71
14
LLPS-Xim-2651
ENSXMAG00000000969.2
M3ZFH4
15
LLPS-Xim-0512
ENSXMAG00000027291.1
A0A3B5QKS8
CPSF3 (1 of many)
16
LLPS-Xim-2933
ENSXMAG00000014187.2
A0A3B5QK62
CTCF
17
LLPS-Xim-2279
ENSXMAG00000007658.2
M3ZZN6
H2AFZ
18
LLPS-Xim-1735
ENSXMAG00000015716.2
Q92143
tp53