Theobroma cacao      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Thc-0165
TCM_006944
A0A061DZH0
TCM_006944
2
LLPS-Thc-1309
TCM_014995
A0A061G7F2
TCM_014995
3
LLPS-Thc-0541
TCM_015191
A0A061G872
TCM_015191
4
LLPS-Thc-1851
TCM_021691
A0A061EQB5
TCM_021691
5
LLPS-Thc-0015
TCM_037551
A0A061GT44
TCM_037551
6
LLPS-Thc-1101
TCM_037984
A0A061GP56
TCM_037984