Takifugu rubripes      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Tar-3149
ENSTRUG00000010531.2
H2TPI4
2
LLPS-Tar-3339
ENSTRUG00000019952.1
A0A3B5KNS3
3
LLPS-Tar-1906
ENSTRUG00000013134.2
H2U8Z2
cpsf1
4
LLPS-Tar-0313
ENSTRUG00000003742.2
A0A3B5KAB9
cpsf2
5
LLPS-Tar-1829
ENSTRUG00000024220.1
A0A3B5KKE3
cpsf4
6
LLPS-Tar-0853
ENSTRUG00000017943.2
H2V9V9
ctcf
7
LLPS-Tar-1811
ENSTRUG00000017448.2
H2V692
ctr9
8
LLPS-Tar-2663
ENSTRUG00000023712.1
A0A3B5K2Q9
ddx20
9
LLPS-Tar-3210
ENSTRUG00000001545.2
H2RTS7
fip1l1
10
LLPS-Tar-1571
ENSTRUG00000016621.2
H2UZY7
hinfp
11
LLPS-Tar-3814
ENSTRUG00000002973.2
H2S3H5
LOC101075369
12
LLPS-Tar-1923
ENSTRUG00000007030.2
H2SXX9
LOC101075419
13
LLPS-Tar-1865
ENSTRUG00000020974.1
A0A3B5KIW1
LOC101080230
14
LLPS-Tar-1002
ENSTRUG00000009729.2
H2TID8
lsm11
15
LLPS-Tar-2878
ENSTRUG00000023256.1
A0A3B5KBM8
NPAT
16
LLPS-Tar-0765
ENSTRUG00000010202.2
A0A3B5KI64
sympk
17
LLPS-Tar-2725
ENSTRUG00000005638.2
H2SMI5
tnrc18