Sus scrofa      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Sus-2307
ENSSSCG00000023045.2
I3L5Y2
BAHCC1
2
LLPS-Sus-1300
ENSSSCG00000004331.4
F1RY19
CASP8AP2
3
LLPS-Sus-0250
ENSSSCG00000005906.4
F1RSN8
CPSF1
4
LLPS-Sus-2814
ENSSSCG00000002447.3
F1SD85
CPSF2
5
LLPS-Sus-0628
ENSSSCG00000020799.2
I3LKR1
CPSF3
6
LLPS-Sus-3522
ENSSSCG00000026896.2
I3LCK9
CPSF4
7
LLPS-Sus-1359
ENSSSCG00000024253.2
I3LDG5
CTCF
8
LLPS-Sus-2675
ENSSSCG00000013406.3
F1S6V3
CTR9
9
LLPS-Sus-0932
ENSSSCG00000006783.3
F1SBP3
DDX20
10
LLPS-Sus-1663
ENSSSCG00000031636.1
A0A287ACH9
FIP1L1
11
LLPS-Sus-2076
ENSSSCG00000006510.3
I3LTR2
GON4L
12
LLPS-Sus-2113
ENSSSCG00000015112.3
F1SAH3
HINFP
13
LLPS-Sus-1052
ENSSSCG00000016738.3
F2Z5P1
LOC100512448
14
LLPS-Sus-2073
ENSSSCG00000038916.1
A0A287B594
LSM10
15
LLPS-Sus-1458
ENSSSCG00000038248.1
A0A287A3H2
LSM11
16
LLPS-Sus-2289
ENSSSCG00000026959.2
I3LF48
NPAT
17
LLPS-Sus-3328
ENSSSCG00000003093.3
F1RM40
SYMPK
18
LLPS-Sus-0826
ENSSSCG00000017950.3
Q9TUB2
TP53