Schizosaccharomyces cryophilus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Scc-1426
SPOG_01665
S9W1X7
SPOG_01665
2
LLPS-Scc-1328
SPOG_02108
S9W2P6
SPOG_02108
3
LLPS-Scc-1189
SPOG_02711
S9W0E8
SPOG_02711
4
LLPS-Scc-0708
SPOG_03978
S9XA98
SPOG_03978
5
LLPS-Scc-0581
SPOG_04263
S9WXI6
SPOG_04263
6
LLPS-Scc-1373
SPOG_04270
S9VTL1
SPOG_04270
7
LLPS-Scc-0419
SPOG_04437
S9VSQ0
SPOG_04437