Pelodiscus sinensis      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Pes-0503
ENSPSIG00000005407.1
K7FCV9
2
LLPS-Pes-2084
ENSPSIG00000007306.1
K7FJ22
3
LLPS-Pes-2361
ENSPSIG00000009257.1
K7FQ81
4
LLPS-Pes-1839
ENSPSIG00000006289.1
K7FFI7
CPSF2
5
LLPS-Pes-0715
ENSPSIG00000016144.1
K7GD69
CPSF3
6
LLPS-Pes-2695
ENSPSIG00000011229.1
K7FWN1
CPSF4
7
LLPS-Pes-2131
ENSPSIG00000003593.1
K7F6Y6
CTCF
8
LLPS-Pes-0655
ENSPSIG00000006368.1
K7FFT1
CTR9
9
LLPS-Pes-1371
ENSPSIG00000003636.1
K7F730
DDX20
10
LLPS-Pes-0407
ENSPSIG00000005931.1
K7FEE9
H2AFV
11
LLPS-Pes-1522
ENSPSIG00000014755.1
K7G8E4
HINFP
12
LLPS-Pes-0204
ENSPSIG00000000590.1
K7EXT0
LSM10
13
LLPS-Pes-0259
ENSPSIG00000005234.1
K7FC65
LSM11
14
LLPS-Pes-1195
ENSPSIG00000008841.1
K7FNV8
NPAT
15
LLPS-Pes-0416
ENSPSIG00000015290.1
K7GAF4
SYMPK
16
LLPS-Pes-3187
ENSPSIG00000010641.1
K7FV57
TNRC18
17
LLPS-Pes-0370
ENSPSIG00000013302.1
K7G3P4
TP53