Oreochromis niloticus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 17 genes.  Reviewed (0 or Unreviewed (17

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Orn-0063
ENSONIG00000007676.1
I3JLD2
2
LLPS-Orn-0432
ENSONIG00000016802.1
I3KJ78
3
LLPS-Orn-1313
ENSONIG00000020904.1
I3KYL0
4
LLPS-Orn-1535
ENSONIG00000008502.1
I3JP94
5
LLPS-Orn-2487
ENSONIG00000017657.1
I3KMC0
6
LLPS-Orn-3019
ENSONIG00000012436.1
I3K3H0
7
LLPS-Orn-3237
ENSONIG00000005503.1
I3JDH4
8
LLPS-Orn-0910
ENSONIG00000001609.1
I3IZI0
casp8ap2
9
LLPS-Orn-2060
ENSONIG00000005901.1
I3JEY6
cpsf2
10
LLPS-Orn-0618
ENSONIG00000003694.1
I3J705
CPSF3 (1 of many)
11
LLPS-Orn-2111
ENSONIG00000008495.1
I3JP83
cpsf4
12
LLPS-Orn-2177
ENSONIG00000005736.1
I3JED8
CTCF
13
LLPS-Orn-1216
ENSONIG00000006019.1
I3JFE0
ctr9
14
LLPS-Orn-1402
ENSONIG00000005379.1
I3JD23
hinfp
15
LLPS-Orn-0257
ENSONIG00000008785.1
I3JQ99
LOC100706148
16
LLPS-Orn-0401
ENSONIG00000013769.1
I3K874
LOC100706645
17
LLPS-Orn-2924
ENSONIG00000018962.1
I3KRX9
p53