Neosartorya fischeri      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 7 genes.  Reviewed (0 or Unreviewed (7

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Nef-0144
NFIA_096750
A1DB13
cft1
2
LLPS-Nef-0002
NFIA_040170
A1D0C1
htz1
3
LLPS-Nef-1488
NFIA_008560
A1D186
NFIA_008560
4
LLPS-Nef-1447
NFIA_021820
A1D4Y0
NFIA_021820
5
LLPS-Nef-0925
NFIA_037260
A1CZI2
NFIA_037260
6
LLPS-Nef-0913
NFIA_056460
A1DNC6
NFIA_056460
7
LLPS-Nef-0868
NFIA_067580
A1D797
NFIA_067580