Melampsora laricipopulina      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Mel-1133
MELLADRAFT_117867
F4S2C6
MELLADRAFT_117867
2
LLPS-Mel-1000
MELLADRAFT_29924
F4RP44
MELLADRAFT_29924
3
LLPS-Mel-0921
MELLADRAFT_38438
F4RY57
MELLADRAFT_38438
4
LLPS-Mel-0165
MELLADRAFT_77838
F4RMH4
MELLADRAFT_77838
5
LLPS-Mel-1265
MELLADRAFT_90299
F4RWF7
MELLADRAFT_90299
6
LLPS-Mel-0069
MELLADRAFT_96156
F4SB62
MELLADRAFT_96156