Medicago truncatula      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 6 genes.  Reviewed (0 or Unreviewed (6

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Met-1095
MTR_2g006180
G7IPE5
11424192
2
LLPS-Met-1400
MTR_1g011750
G7I6D5
11429815
3
LLPS-Met-0002
MTR_1g050492
A0A072VI07
25483257
4
LLPS-Met-1701
MTR_2g041420
A0A072V869
25486489
5
LLPS-Met-1960
MTR_4g015850
A0A072UGV2
25491448
6
LLPS-Met-0739
MTR_6g461810
A0A072UAN0
25497136