Lepisosteus oculatus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Leo-0164
ENSLOCG00000016823.1
W5NJI7
2
LLPS-Leo-0269
ENSLOCG00000013832.1
W5N8V4
3
LLPS-Leo-0278
ENSLOCG00000007268.1
W5MK96
4
LLPS-Leo-0374
ENSLOCG00000004756.1
W5MBE9
5
LLPS-Leo-0383
ENSLOCG00000003801.1
W5M833
6
LLPS-Leo-0564
ENSLOCG00000004814.1
W5MBM3
7
LLPS-Leo-0661
ENSLOCG00000008484.1
W5MPM7
8
LLPS-Leo-0791
ENSLOCG00000006895.1
W5MIX9
9
LLPS-Leo-1133
ENSLOCG00000015274.1
W5NDT6
10
LLPS-Leo-1190
ENSLOCG00000016949.1
W5NJZ3
11
LLPS-Leo-1275
ENSLOCG00000009264.1
W5MSD8
12
LLPS-Leo-1645
ENSLOCG00000014228.1
W5NA60
13
LLPS-Leo-2019
ENSLOCG00000003894.1
W5M8E1
14
LLPS-Leo-2301
ENSLOCG00000010372.1
W5MWF7
15
LLPS-Leo-2515
ENSLOCG00000014102.1
W5N9R8
16
LLPS-Leo-2549
ENSLOCG00000018277.1
W5NP19
17
LLPS-Leo-2752
ENSLOCG00000001312.1
W5LZE2
18
LLPS-Leo-3932
ENSLOCG00000014127.1
W5N9V5