Ictalurus punctatus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 18 genes.  Reviewed (0 or Unreviewed (18

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Icp-1735
ENSIPUG00000010358.1
W5U8I7
Casp8ap2
2
LLPS-Icp-0100
ENSIPUG00000011259.1
A0A2D0PWK1
cpsf1
3
LLPS-Icp-2502
ENSIPUG00000020857.1
A0A2D0Q0G2
cpsf2
4
LLPS-Icp-0963
ENSIPUG00000023488.1
A0A2D0PZ44
cpsf3
5
LLPS-Icp-1943
ENSIPUG00000017147.1
E3TFL1
CPSF4
6
LLPS-Icp-2536
ENSIPUG00000003840.1
A0A2D0QSV0
ctcf
7
LLPS-Icp-0762
ENSIPUG00000010291.1
W5U5U5
CTR9
8
LLPS-Icp-0088
ENSIPUG00000004876.1
W5UEH5
ddx20
9
LLPS-Icp-0038
ENSIPUG00000016307.1
E3TFA0
H2AV
10
LLPS-Icp-3950
ENSIPUG00000008809.1
A0A2D0QEP7
hinfp
11
LLPS-Icp-2406
ENSIPUG00000022454.1
A0A2D0QGS8
LOC108260848
12
LLPS-Icp-2137
ENSIPUG00000004414.1
A0A2D0RC02
LOC108267623
13
LLPS-Icp-2560
ENSIPUG00000004800.1
A0A2D0SWN9
LOC108278318
14
LLPS-Icp-2885
ENSIPUG00000005808.1
W5UCI5
Lsm10
15
LLPS-Icp-4241
ENSIPUG00000018086.1
A0A2D0RG25
lsm11
16
LLPS-Icp-1399
ENSIPUG00000024020.1
W5U6I2
SYMPK
17
LLPS-Icp-3848
ENSIPUG00000017314.1
W5UEY6
Tnrc18
18
LLPS-Icp-2831
ENSIPUG00000021439.1
O93379
tp53