Gasterosteus aculeatus      Histone locus body


※ Histone locus body introduction

    The histone locus body (HLB) contains factors required for processing histone pre-mRNAs, which is present throughout the interphase of the cell cycle, but disappear during mitosis. It is associated with the genes that code for histones, suggesting that it may function to concentrate processing factors at their site of action (1). Besides, as one of the coilin-containing bodies like Cajal bodies , HLB in nuclei of late two-cell embryos are heterogeneous in both morphology and molecular composition, but their heterogeneity is not related to the number of coilin-positive intranuclear HLB structures (2).

Reference
1. Nizami, Z., Deryusheva, S., & Gall, J. G. (2010) The Cajal body and histone locus body. Cold Spring Harb Perspect Biol, 2(7), a000653. PMID: 20504965
2. Bogolyubova, I. O. (2017) Heterogeneity of Coilin-Containing Nuclear Domains in Early Mouse Embryos. Tsitologiia, 59(4), 290-297. PMID: 30188094


There are 16 genes.  Reviewed (0 or Unreviewed (16

No.StatusDrLLPS IDEnsemble Gene IDUniProt AccessionGene Name
1
LLPS-Gaa-0067
ENSGACG00000015946.1
G3PTV6
2
LLPS-Gaa-0339
ENSGACG00000008703.2
G3P1Y1
3
LLPS-Gaa-0436
ENSGACG00000018447.2
G3Q3D7
4
LLPS-Gaa-0630
ENSGACG00000008418.1
G3P0K7
5
LLPS-Gaa-1128
ENSGACG00000003088.1
G3NFE6
6
LLPS-Gaa-1217
ENSGACG00000015700.1
G3PSY3
7
LLPS-Gaa-1289
ENSGACG00000014618.1
G3PNW6
8
LLPS-Gaa-1459
ENSGACG00000020411.1
G3QAR7
9
LLPS-Gaa-1515
ENSGACG00000002329.1
G3NCH9
10
LLPS-Gaa-1725
ENSGACG00000002735.1
G3NE42
11
LLPS-Gaa-1837
ENSGACG00000007811.1
G3NYD6
12
LLPS-Gaa-1917
ENSGACG00000001440.1
G3N9A2
13
LLPS-Gaa-2519
ENSGACG00000007792.1
G3NYA8
14
LLPS-Gaa-2613
ENSGACG00000006239.1
G3NSD3
15
LLPS-Gaa-3265
ENSGACG00000015865.1
G3PTK5
16
LLPS-Gaa-1881
ENSGACG00000007005.1
G3NVA7
NPAT